Friday, November 11, 2011

My Third PCR (Polymerase Chain Reaction Test)


My Daughter and four of five grand-kids!

What I have come to understand, is that the best way to measure the burden of disease (leukemia) in your body is to monitor Bcr-Abl RNA or DNA in the blood and bone marrow. The goal is for the Bcr-Abl to eventually become undetectable.

It seems to be that a person that starts their treatment on Sprycel (Dasatinib) tends to reach these milestones, a bit quicker than if they were to begin their treatment with Gleevec (Imatinib). My first PCR results, were five months ago, in May 2011, and the reading was 5.9 x 10-2. My last results are in and I have reached 3.99 x 10-4. This is a significant improvement and I have reached it in record time. Next test will be in December. I am hoping for a terrific Christmas surprise of my numbers coming in in the negative category!
Thanks for the continued support and prayers!

5 comments:

  1. mICHELLE GLAD TO HEAR YOUR NUMBERS ARE GOING THE RIGHT DIRECTION. i HAVE BEEN ON GLIVEC SINCE OCTOBER 2009 hAVEN'T REACHED pcru bUT HAVE hAD MMR AFTER 9 MONTHS. HOPE YOU AND YOUR FAMILY ARE KEEPING WELL.LOVE READING YOUR BLOG.

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  2. well, thanks, I wish you the best two, sounds like you are a little over a year ahead of me!

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  3. Wow, congratulations! You will be undetectable before you know it. Hmmmmmm, maybe I need to switch to Spycel! I am on Gleevec and although I am responding faster than the norm, it definitely isn't as fast as your response. So very happy that you are doing well. :-)

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  4. When is it considered undectable? >.0001 ???

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  5. I am not sure "when" undetectable is achieved!
    And Dan if you switch to Sprycel and make less than $75,000 and your insurance does not cover it, Contact me. I get my meds from Bristol-Myer Squibb no charge.

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Bricks for the Brave!!